Roxana (Greek: Ρωξάνη; Old Iranian Raoxshna; sometimes Roxanne, Roxanna, Roxandra and Roxane), was a Bactrian princess and a wife of Alexander the Great. She was born earlier than the year 343 BC, though the precise date remains uncertain, and died in ca. 310 BC.
Roxana was the daughter of a minor Bactrian baron named Oxyartes of Balkh in Bactria (around the modern-day Balkh province of Afghanistan). In 327 BC Alexander the Great married Roxana despite the strong opposition from all his companions and generals. She was pregnant with his son Alexander IV when he died unexpectedly. She and her son soon became pawns of the various factions battling for their stake in Alexander the Great's empire. She and her son were both poisoned on the orders of the general Cassander, who wanted to take Macedon for himself.