Manuel is a Spanish-Portuguese variation of Immanuel/Emmanuel, a Hebrew given name meaning "God with (or 'among') us". In the works of Harry Turtledove, it may refer to:

Characters named Manuel:

Manuel (Eyewear), an Aztec character in "Eyewear"
Manuel (Southern Victory), a Mexican dishwasher and minor character in Drive to the East.
Manuel José Acevedo, fictional American serviceman, minor character in The Man With the Iron Heart.
Manuel Azaña, a historical Spanish politician appearing in Last Orders.

Characters named Manny:

Manny (Iron Heart), an American soldier and minor character in The Man With the Iron Heart.

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