Isaac or Isaak, transliterated from (Hebrew: יִצְחָק‎, Standard Yiẓḥaq Tiberian Yiṣḥāq, Arabic: إسحٰق‎ ʾIsḥāq) as Itzhak or Yitzhak, or Yitzchok, was one of the three patriarchs in the Hebrew Bible, whose story is told in the book of Genesis.

In the works of Harry Turtledove, Isaac may refer to:

Characters known only by the name Isaac:

Isaac (Freedom), an activist in "Freedom" from A Different Flesh.
Isaac (Departures), an abbot in "Departures".

Characters whose first or middle name is Isaac:

Isaac Asimov, a historical science and Science Fiction author, a creator of some shared universes to which Turtledove contributed.
Isaac Cockrell, historical Confederate soldier appearing in The Guns of the South.
Isaac Fenner, a fictional politician in The United States of Atlantis.
Isaac Hamburger, minor fictional character in Southern Victory.
Isaac Hawkins, a historical politician and soldier referenced in Fort Pillow.
Isaac Kabasilas, a minor character in "Unholy Trinity".
Isaac Komnenos, a historical Byzantine general appearing in "Two Thieves".
Daniel I.J. Thornton, historical Colorado Governor referenced in Bombs Away.

Characters known only by the name Yitzhak or a variant spelling:

Yitzkhak (The More it Changes), the POV of "The More it Changes".
Yitzkhak (The Hot War), a displaced person and minor character in The Hot War.
Yitzkhak (Worldwar), a partisan and minor character in Striking the Balance.
Itzhak Zalman, fictional athlete in "Les Mortes d'Arthur".

Miscellaneous uses of Isaac:

Isaac's Universe, story setting created by Isaac Asimov for other authors (including Harry Turtledove) to use.

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