Houston, in the works of Harry Turtledove, may refer to:


Sam Houston, a historical general and politician, referenced in "Lee at the Alamo" and The Great War: Breakthroughs.
John Houston Thorpe, a historical Confederate soldier and historian who appears in "The Last Reunion" and The Guns of the South.


Houston, Texas, a large American city named for Sam Houston. It plays a role as a city in the Confederate States in Southern Victory.
Houston (State), a fictional state of the United States, named for Sam Houston and carved out from northwest Texas, and a setting in the Southern Victory series.


"Houston, We Have a Problem", a fictional work of fiction in "Hindsight."