Claudia Pulchra (English: Claudia the Good-looking, 14 BC-26) was a patrician woman of Ancient Rome who lived during the reigns of Emperors Augustus and Tiberius. She was the daughter of Claudia Marcella Minor and Claudius Pulcher, by adoption Marcus Valerius Messala Barbatus Appianus, who was Consul in 12 BC and died in office. Her maternal grandparents were Gaius Claudius Marcellus Minor and Octavia Minor, sister of Augustus. Her father, Marcus Valerius Messala Barbatus Appianus was a son of consul Appius Claudius Pulcher, Consul in 38 BC. Her mother married Roman senator Marcus Valerius Messalla Messallinus. She was the elder half sister of Marcus Valerius Messalla Barbatus (who would later become the father of Valeria Messalina, third wife of Emperor Claudius).
Claudia Pulchra was the grand-niece of Augustus and married to Publius Quinctilius Varus. In AD 7 Varus was assigned to be the military governor of Germany. This appointment to such a barbaric land outraged Claudia but since Augustus ordered it, she had to accept it. Nevertheless, she refused to accompany her husband as she had previously to Syria.